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Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice

Misexpression of microRNAs (miRNAs) is widespread in human cancers, including in pancreatic cancer. Aberrations of miRNA include overexpression of oncogenic miRs ("Onco-miRs"), or downregulation of so-called tumor suppressor "TSG-miRs". Restitution of TSG-miRs in cancer cells thr...

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Detalhes bibliográficos
Main Authors: Pramanik, Dipankar, Campbell, Nathaniel R., Karikari, Collins, Chivukula, Raghu, Kent, Oliver A., Mendell, Joshua T., Maitra, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154495/
https://ncbi.nlm.nih.gov/pubmed/21622730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0152
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