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The heat-stable antigen determines pathogenicity of self-reactive T cells in experimental autoimmune encephalomyelitis

Induction of myelin-specific CD4 T cells is a pivotal event in the development of experimental autoimmune encephalomyelitis (EAE). Other checkpoints in EAE pathogenesis have not been clearly defined, although multiple genetic loci are known to influence EAE development. We report here that targeted...

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Autors principals: Bai, Xue-Feng, Liu, Jin-Qing, Liu, Xingluo, Guo, Yong, Cox, Karen, Wen, Jing, Zheng, Pan, Liu, Yang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC315444/
https://ncbi.nlm.nih.gov/pubmed/10791997
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