Pancreatic Neuroendocrine Tumors in Glucagon Receptor-Deficient Mice

Inhibition of glucagon signaling causes hyperglucagonemia and pancreatic α cell hyperplasia in mice. We have recently demonstrated that a patient with an inactivating glucagon receptor mutation (P86S) also exhibits hyperglucagonemia and pancreatic α cell hyperplasia but further develops pancreatic n...

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Main Authors: Yu, Run, Dhall, Deepti, Nissen, Nicholas N., Zhou, Cuiqi, Ren, Song-Guang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154424/
https://ncbi.nlm.nih.gov/pubmed/21853126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023397
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