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Naloxone-induced cortisol predicts mu opioid receptor binding potential in specific brain regions of healthy subjects

Investigators have administered the opioid receptor antagonist, naloxone, to interrogate the hypothalamic-pituitary-adrenal (HPA) axis response under the assumption that this technique provides a measure of endogenous opioid activity. However it has never been tested whether provocation of the HPA a...

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Autori principali: Wand, Gary S., Weerts, Elise M., Kuwabara, Hiroto, Frost, J. James, Xu, Xiaoqiang, McCaul, Mary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154371/
https://ncbi.nlm.nih.gov/pubmed/21549509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2011.03.019
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