Corticotropin-releasing hormone links pituitary adrenocorticotropin gene expression and release during adrenal insufficiency

Corticotropin-releasing hormone (CRH)–deficient (KO) mice provide a unique system to define the role of CRH in regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Despite several manifestations of chronic glucocorticoid insufficiency, basal pituitary proopiomelanocortin (POMC) mRNA, adrenoc...

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Udgivet i:J Clin Invest
Main Authors: Muglia, Louis J., Jacobson, Lauren, Luedke, Christina, Vogt, Sherri K., Schaefer, Michele L., Dikkes, Pieter, Fukuda, Shoko, Sakai, Yoko, Suda, Toshihiro, Majzoub, Joseph A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5250
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