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Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors

Protein Inhibitor of Activated Signal Transducer and Activators of Transcription 3 (PIAS3) is a molecule that regulates STAT3 and has antiproliferative properties. Glioblastoma and squamous cell lung cancer lack PIAS3 expression. To test the hypothesis that PIAS3 transcriptional effects are STAT3-in...

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Bibliografische gegevens
Hoofdauteurs: Dabir, Snehal, Kluge, Amy, Aziz, Mohammad A, Houghton, Janet A, Dowlati, Afshin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154286/
https://ncbi.nlm.nih.gov/pubmed/21532337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.2.15732
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