Targeted Over-Expression of Glutamate Transporter 1 (GLT-1) Reduces Ischemic Brain Injury in a Rat Model of Stroke

Following the onset of an ischemic brain injury, the excitatory neurotransmitter glutamate is released. The excitotoxic effects of glutamate are a major contributor to the pathogenesis of a stroke. The aim of this study was to examine if overexpression of a glutamate transporter (GLT-1) reduces isch...

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Detalhes bibliográficos
Main Authors: Harvey, Brandon K., Airavaara, Mikko, Hinzman, Jason, Wires, Emily M., Chiocco, Matthew J., Howard, Douglas B., Shen, Hui, Gerhardt, Greg, Hoffer, Barry J., Wang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154194/
https://ncbi.nlm.nih.gov/pubmed/21853027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022135
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