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Hierarchical Differentiation of Myeloid Progenitors Is Encoded in the Transcription Factor Network

Hematopoiesis is an ideal model system for stem cell biology with advanced experimental access. A systems view on the interactions of core transcription factors is important for understanding differentiation mechanisms and dynamics. In this manuscript, we construct a Boolean network to model myeloid...

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Détails bibliographiques
Auteurs principaux: Krumsiek, Jan, Marr, Carsten, Schroeder, Timm, Theis, Fabian J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154193/
https://ncbi.nlm.nih.gov/pubmed/21853041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022649
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