Intrinsic resistance to tyrosine kinase inhibitors is associated with poor clinical outcome in metastatic renal cell carcinoma

BACKGROUND: Data on sequential therapy in patients with metastatic renal cell carcinoma (mRCC) and intrinsic resistance to receptor tyrosine kinase inhibitor (rTKI) treatment remains vague. METHODS: We retrospectively studied treatment characteristics and outcome of mRCC patients refractory to first...

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Autores principales: Busch, Jonas, Seidel, Christoph, Weikert, Steffen, Wolff, Ingmar, Kempkensteffen, Carsten, Weinkauf, Lisa, Hinz, Stefan, Magheli, Ahmed, Miller, Kurt, Grünwald, Viktor
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154177/
https://ncbi.nlm.nih.gov/pubmed/21756335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-295
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