Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequences

BACKGROUND: Renal kallikrein (KLK1) synthesis and urinary excretion are reportedly diminished during AKI (acute kidney injury) in animal models, and provision of kallikrein abrogates renal injury in this setting, but data in human AKI is limited. Therefore we first examined KLK1 renal excretion in h...

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Detalhes bibliográficos
Main Authors: Kang, Sun Woo, Shih, Pei-an Betty, Mathew, Roy O, Mahata, Manjula, Biswas, Nilima, Rao, Fangwen, Yan, Liying, Bouchard, Josee, Malhotra, Rakesh, Tolwani, Ashita, Khandrika, Srikrishna, Mehta, Ravindra L, O'Connor, Daniel T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154145/
https://ncbi.nlm.nih.gov/pubmed/21679467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-12-27
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