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Steric effects on the enantiodiscrimination of diproline chiral stationary phases in the resolution of racemic compounds

Eight diproline chiral stationary phases with different end-capping groups were prepared and evaluated for the enantio-selective resolution of 41 racemic analytes. The end-capping group on the N-terminal of the peptide proved to be important as the chiral separation efficiency was decreased signific...

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Autors principals: Dai, Zhi, Ye, Guozhong, Pittman, Charles U., Li, Tingyu
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154017/
https://ncbi.nlm.nih.gov/pubmed/21741656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2011.06.047
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