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Metal-Substituted Protein MRI Contrast Agents Engineered for Enhanced Relaxivity and Ligand Sensitivity

Engineered metalloproteins constitute a flexible new class of analyte-sensitive molecular imaging agents detectable by magnetic resonance imaging (MRI), but their contrast effects are generally weaker than synthetic agents. To augment the proton relaxivity of agents derived from the heme domain of c...

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Bibliografische gegevens
Hoofdauteurs: Lelyveld, Victor S., Brustad, Eric, Arnold, Frances H., Jasanoff, Alan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154012/
https://ncbi.nlm.nih.gov/pubmed/21171606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107936d
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