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Genetic Mutations and Mitochondrial Toxins Shed New Light on the Pathogenesis of Parkinson's Disease

The cellular abnormalities in Parkinson's disease (PD) include mitochondrial dysfunction and oxidative damage, which are probably induced by both genetic predisposition and environmental factors. Mitochondrial dysfunction has long been implicated in the pathogenesis of PD. The recent discovery...

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Hlavní autoři: Sato, Shigeto, Hattori, Nobutaka
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE-Hindawi Access to Research 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153940/
https://ncbi.nlm.nih.gov/pubmed/21860779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/979231
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