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Memantine in Systemic Lupus Erythematosus: A Randomized, Double-Blind Placebo-Controlled Trial

OBJECTIVES: Cognitive impairment affects up to 80% of systemic lupus erythematosus (SLE) patients within ten years of diagnosis. Memantine, a seronergic receptor and nicotine acetylcholine receptor antagonist, acts on the glutamatergic system through the NMDA receptor, and is used to treat dementia....

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Detalhes bibliográficos
Main Authors: Petri, Michelle, Naqibuddin, Mohammad, Sampedro, Margaret, Omdal, Roald, Carson, Kathryn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153605/
https://ncbi.nlm.nih.gov/pubmed/21458845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semarthrit.2011.02.005
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