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A Double Blind, Placebo-Controlled, Randomized Crossover Study of the Acute Metabolic Effects of Olanzapine in Healthy Volunteers

BACKGROUND AND RATIONALE: Atypical antipsychotics exhibit metabolic side effects including diabetes mellitus and obesity. The adverse events are preceded by acute worsening of oral glucose tolerance (oGTT) along with reduced plasma free fatty acids (FFA) and leptin in animal models. It is unclear wh...

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Detalhes bibliográficos
Main Authors: Albaugh, Vance L., Singareddy, Ravi, Mauger, David, Lynch, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153475/
https://ncbi.nlm.nih.gov/pubmed/21857944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022662
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