CD4(+)CD25(+) Regulatory Cells Contribute to the Regulation of Colonic Th2 Granulomatous Pathology Caused by Schistosome Infection

Eggs of the helminth Schistosoma mansoni accumulate in the colon following infection and generate Th2-biassed inflammatory granulomas which become down- modulated in size as the infection proceeds to chronicity. However, although CD4(+)CD25(+)FoxP3(+)regulatory T cells (T(regs)) are known to suppres...

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Detalhes bibliográficos
Main Authors: Turner, Joseph D., Jenkins, Gavin R., Hogg, Karen G., Aynsley, Sarah A., Paveley, Ross A., Cook, Peter C., Coles, Mark C., Mountford, Adrian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153428/
https://ncbi.nlm.nih.gov/pubmed/21858239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001269
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