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A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a CAG repeat expansion in exon 1 of huntingtin (HTT). Relatively little attention has been directed to the genomic features of the antisense strand at the HD locus, though the presence of a transcript from this stra...

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Autors principals: Chung, Daniel W., Rudnicki, Dobrila D., Yu, Lan, Margolis, Russell L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153309/
https://ncbi.nlm.nih.gov/pubmed/21672921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr263
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