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Novel Cytotoxic Vectors Based on Adeno-Associated Virus

Vectors based on adeno-associated virus (AAV) are promising tools for gene therapy. The production of strongly toxic vectors, for example for cancer-directed gene transfer, is often unfeasible due to uncontrolled expression of toxic genes in vector-producing cells. Using an approach based on transcr...

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Hlavní autoři: Kohlschütter, Johannes, Michelfelder, Stefan, Trepel, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153187/
https://ncbi.nlm.nih.gov/pubmed/22069574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2122754
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