Ribosome-Inactivating Proteins: From Plant Defense to Tumor Attack

Ribosome-inactivating proteins (RIPs) are EC3.2.32.22 N-glycosidases that recognize a universally conserved stem-loop structure in 23S/25S/28S rRNA, depurinating a single adenine (A4324 in rat) and irreversibly blocking protein translation, leading finally to cell death of intoxicated mammalian cell...

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Bibliografiske detaljer
Main Authors: de Virgilio, Maddalena, Lombardi, Alessio, Caliandro, Rocco, Fabbrini, Maria Serena
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2010
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153179/
https://ncbi.nlm.nih.gov/pubmed/22069572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2112699
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