טוען...

Down-regulation of heat shock protein 70 improves arsenic trioxide and 17-DMAG effects on constitutive signal transducer and activator of transcription 3 activity

PURPOSE: Signal transducer and activator of transcription 3 (STAT3) has been shown to be constitutively active in approximately 50% of patients with acute myeloid leukemia and is associated with worse outcome. Arsenic trioxide (ATO) synergizes with the heat shock protein (HSP) 90 inhibitor, 17-DMAG,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ghoshal, Sampa, Rao, Indranil, Earp, Justin C., Jusko, William J., Wetzler, Meir
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152797/
https://ncbi.nlm.nih.gov/pubmed/20035426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1210-7
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