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Regulation and function of IL-17A- and IL-22-producing γδ T cells
The regulation of IL-17A and IL-22 production differs between human and murine γδ T cells. We find that human γδ T cells expressing Vγ2Vδ2 T cell receptors are peripherally polarized to produce IL-17A or IL-22, much like CD4 αβ Th17 T cells. This requires IL-6, IL-1β, and TGF-β, whereas expansion an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152582/ https://ncbi.nlm.nih.gov/pubmed/21573786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0700-z |
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