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Tiotropium reduces risk of exacerbations irrespective of previous use of inhaled anticholinergics in placebo-controlled clinical trials

BACKGROUND: Data have highlighted the potential bias introduced by withdrawal of inhaled corticosteroids at randomization in chronic obstructive pulmonary disease trials examining inhaled corticosteroids. Analyses were conducted to determine whether this was true of inhaled anticholinergic withdrawa...

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Main Authors: Cooper, Christopher B, Anzueto, Antonio, Decramer, Marc, Celli, Bartolome, Tashkin, Donald P, Leimer, Inge, Kesten, Steven
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152465/
https://ncbi.nlm.nih.gov/pubmed/21845038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S17864
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