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Myocyte Specific Overexpression of Myoglobin Impairs Angiogenesis After Hind-Limb Ischemia

OBJECTIVE: In preclinical models of peripheral arterial disease the angiogenic response is typically robust, though it can be impaired in conditions such as hypercholesterolemia and diabetes where the endothelium is dysfunctional. Myoglobin (Mb) is expressed exclusively in striated muscle cells. We...

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Autors principals: Hazarika, Surovi, Angelo, Michael, Li, Yongjun, Aldrich, Amy J., Odronic, Shelley I., Yan, Zhen, Stamler, Jonathan S., Annex, Brian H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152376/
https://ncbi.nlm.nih.gov/pubmed/18818418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.170951
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