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Mechanistic analysis of Xenopus EXO1's function in 5′-strand resection at DNA double-strand breaks
The processing of DNA double-strand breaks (DSBs) into 3′ single-stranded tails is the first step of homology-dependent DSB repair. A key player in this process is the highly conserved eukaryotic exonuclease 1 (EXO1), yet its precise mechanism of action has not been rigorously determined. To address...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152354/ https://ncbi.nlm.nih.gov/pubmed/21490081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr216 |
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