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A Polarized Epithelium Organized by β- and α-Catenin Predates Cadherin and Metazoan Origins
A polarized epithelium in the non-metazoan Dictyostelium discoideum requires α-catenin and β-catenin but not classical cadherins, polarity proteins or Wnt signaling. A fundamental characteristic of metazoans is the formation of a simple, polarized epithelium. In higher animals, the structural integr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152298/ https://ncbi.nlm.nih.gov/pubmed/21393547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1199633 |
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