FGF23 Fails to Inhibit Uremic Parathyroid Glands

Fibroblast growth factor 23 (FGF23) modulates mineral metabolism by promoting phosphaturia and decreasing the production of 1,25-dihydroxyvitamin D(3). FGF23 decreases parathyroid hormone (PTH) mRNA and secretion, but despite a marked elevation in FGF23 in uremia, PTH production increases. Here, we...

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Detalhes bibliográficos
Main Authors: Canalejo, Rocío, Canalejo, Antonio, Martinez-Moreno, Julio Manuel, Rodriguez-Ortiz, M. Encarnacion, Estepa, Jose C., Mendoza, Francisco Javier, Munoz-Castaneda, Juan Rafael, Shalhoub, Victoria, Almaden, Yolanda, Rodriguez, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152229/
https://ncbi.nlm.nih.gov/pubmed/20431039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009040427
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