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Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver

Orotic acid (OA), an intermediate in pyrimidine metabolism, has been used for a variety of purposes, such as dietary supplements. Although it is well documented that OA induces fatty liver in a species-specific manner, the precise molecular mechanisms remain unclear. The present study investigated t...

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Main Authors: Jung, Eun-Jeong, Kwon, Sung-Won, Jung, Byung-Hwa, Oh, Seon-Hee, Lee, Byung-Hoon
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151682/
https://ncbi.nlm.nih.gov/pubmed/21757781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M015263
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