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Size and Sequence and the Volume Change of Protein Folding
The application of hydrostatic pressure generally leads to protein unfolding, implying, in accordance to LeChatelier’s principle, that the unfolded state has smaller molar volume than the folded state. However, the origin of the volume change upon unfolding, ΔVu, has yet to be determined. We have ex...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151578/ https://ncbi.nlm.nih.gov/pubmed/21446709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja200228w |
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