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Neuroprotective Effect of Uncaria rhynchophylla in Kainic Acid-Induced Epileptic Seizures by Modulating Hippocampal Mossy Fiber Sprouting, Neuron Survival, Astrocyte Proliferation, and S100B Expression

Uncaria rhynchophylla (UR), which is a traditional Chinese medicine, has anticonvulsive effect in our previous studies, and the cellular mechanisms behind this are still little known. Because of this, we wanted to determine the importance of the role of UR on kainic acid- (KA-) induced epilepsy. Ora...

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Hlavní autoři: Liu, Chung-Hsiang, Lin, Yi-Wen, Tang, Nou-Ying, Liu, Hsu-Jan, Hsieh, Ching-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151516/
https://ncbi.nlm.nih.gov/pubmed/21837247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/194790
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