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Use of parthenogenetic activation of human oocytes as an experimental model for evaluation of polar body based PGD assay performance

PURPOSE: To develop an experimental model to assess the feasibility of polar body preimplantation genetic diagnosis without requiring oocyte fertilization. METHODS: First polar body was removed from donated oocytes and second polar body was biopsied after parthenogenetic activation. Molecular analys...

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Detalhes bibliográficos
Main Authors: Paffoni, Alessio, Paracchini, Valentina, Ferrari, Stefania, Scarduelli, Claudia, Seia, Manuela, Coviello, Domenico A., Ragni, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151362/
https://ncbi.nlm.nih.gov/pubmed/21360136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-011-9540-x
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