Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models

We investigated the therapeutic potential of human bone marrow-derived mesenchymal stem cells (hBM-MSCs) in Huntington's disease (HD) mouse models. Ten weeks after intrastriatal injection of quinolinic acid (QA), mice that received hBM-MSC transplantation showed a significant reduction in motor...

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Détails bibliographiques
Auteurs principaux: Lin, Yuan-Ta, Chern, Yijuang, Shen, Che-Kun James, Wen, Hsin-Lan, Chang, Ya-Chin, Li, Hung, Cheng, Tzu-Hao, Hsieh-Li, Hsiu Mei
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151281/
https://ncbi.nlm.nih.gov/pubmed/21850243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022924
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