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Acid Ceramidase Expression Modulates the Sensitivity of A375 Melanoma Cells to Dacarbazine

Dacarbazine (DTIC) is the treatment of choice for metastatic melanoma, but its response in patients remains very poor. Ceramide has been shown to be a death effector and to play an important role in regulating cancer cell growth upon chemotherapy. Among ceramidases, the enzymes that catabolize ceram...

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Bibliografski detalji
Glavni autori: Bedia, Carmen, Casas, Josefina, Andrieu-Abadie, Nathalie, Fabriàs, Gemma, Levade, Thierry
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151065/
https://ncbi.nlm.nih.gov/pubmed/21700700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216382
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