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Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting
Many drugs are nature derived. Low drug productivity has renewed interest in natural products as drug-discovery sources. Nature-derived drugs are composed of dozens of molecular scaffolds generated by specific secondary-metabolite gene clusters in selected species. It can be hypothesized that drug-l...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150889/ https://ncbi.nlm.nih.gov/pubmed/21768386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107336108 |
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