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Application of a water-soluble pyridyl disulfide amine linker for use in Cu-free click bioconjugation
Described herein is the design and synthesis of a discrete heterobifunctional PEG-based pyridyl disulfide/amine-containing linker that can be used in the Cu-free click preparation of bioconjugates. The title PEG-based pyridyl disulfide amine linker is a potentially useful reagent for preparing water...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150709/ https://ncbi.nlm.nih.gov/pubmed/21826118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.06.042 |
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