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Genetic LRRK2 Models of Parkinson’s Disease: Dissecting Pathogenic pathway and Exploring Clinical Application
Dominantly inherited mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). Understanding LRRK2 biology and pathophysiology is central to the elucidation of PD etiology and development of disease intervention. Recently a number of genetic mo...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150637/ https://ncbi.nlm.nih.gov/pubmed/21538530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23737 |
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