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ARF6-regulated shedding of tumor-cell derived plasma membrane microvesicles

BACKGROUND: Increased MAPK signaling, small GTPase activation, cytoskeletal rearrangements and the directed targeting of proteases to sites of extracellular matrix degradation, all accompany the process of tumor cell invasion. Several studies have implicated the small GTP-binding protein, ARF6, in t...

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Главные авторы: Muralidharan-Chari, Vandhana, Clancy, James, Plou, Carolyn, Romao, Maryse, Chavrier, Philippe, Raposo, Graca, D’Souza-Schorey, Crislyn
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150487/
https://ncbi.nlm.nih.gov/pubmed/19896381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.09.059
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