A Novel Human Ghrelin Variant (In1-Ghrelin) and Ghrelin-O-Acyltransferase Are Overexpressed in Breast Cancer: Potential Pathophysiological Relevance

The human ghrelin gene, which encodes the ghrelin and obestatin peptides, contains 5 exons (Ex), with Ex1-Ex4 encoding a 117 amino-acid (aa) preproprotein that is known to be processed to yield a 28-aa (ghrelin) and/or a 23-aa (obestatin) mature peptides, which possess biological activities in multi...

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Autors principals: Gahete, Manuel D., Córdoba-Chacón, José, Hergueta-Redondo, Marta, Martínez-Fuentes, Antonio J., Kineman, Rhonda D., Moreno-Bueno, Gema, Luque, Raúl M., Castaño, Justo P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150424/
https://ncbi.nlm.nih.gov/pubmed/21829727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023302
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