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Broad Antibody Mediated Cross-Neutralization and Preclinical Immunogenicity of New Codon-Optimized HIV-1 Clade CRF02_AG and G Primary Isolates

Creation of an effective vaccine for HIV has been an elusive goal of the scientific community for almost 30 years. Neutralizing antibodies are assumed to be pivotal to the success of a prophylactic vaccine but previous attempts to make an immunogen capable of generating neutralizing antibodies to pr...

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Autors principals: Agwale, Simon M., Forbi, Joseph C., Notka, Frank, Wrin, Terri, Wild, Jens, Wagner, Ralf, Wolf, Hans
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150420/
https://ncbi.nlm.nih.gov/pubmed/21829720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023233
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