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Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells

BACKGROUND: Autocrine & paracrine signaling are widespread both in vivo and in vitro, and are particularly important in embryonic stem cell (ESC) pluripotency and lineage commitment. Although autocrine signaling via fibroblast growth factor-4 (FGF4) is known to be required in mouse ESC (mESC) ne...

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Detalhes bibliográficos
Main Authors: Blagovic, Katarina, Kim, Lily Y., Voldman, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150375/
https://ncbi.nlm.nih.gov/pubmed/21829665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022892
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