Protective roles for fibrin, tissue factor, PAI-1, and TAFI, but not FXI, during defense against the gram-negative bacterium Yersinia enterocolitica()

Septic infections dysregulate hemostatic pathways, prompting coagulopathy. Nevertheless, anticoagulant therapies typically fail to protect humans from septic pathology. The data reported here may help to explain this discrepancy by demonstrating critical protective roles for coagulation leading to f...

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Detalhes bibliográficos
Main Authors: Luo, Deyan, Szaba, Frank M., Kummer, Lawrence W., Plow, Edward F., Mackman, Nigel, Gailani, David, Smiley, Stephen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150340/
https://ncbi.nlm.nih.gov/pubmed/21724997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101094
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