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Exposure of Neurons to Excitotoxic Levels of Glutamate Induces Cleavage of ADAR2 and Loss of GluR2 Editing
AMPA receptors are glutamate receptors that are tetramers of various combinations of GluR1-4 subunits. AMPA receptors containing GluR1, 3 and 4 are Ca(2+) permeable, however, AMPA receptors containing even a single subunit of GluR2 are Ca(2+) impermeable. Most AMPA receptors are Ca(2+) impermeable d...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150305/ https://ncbi.nlm.nih.gov/pubmed/21620933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.05.027 |
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