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Crystal Structure of PrgI-SipD: Insight into a Secretion Competent State of the Type Three Secretion System Needle Tip and its Interaction with Host Ligands

Many infectious Gram-negative bacteria, including Salmonella typhimurium, require a Type Three Secretion System (T3SS) to translocate virulence factors into host cells. The T3SS consists of a membrane protein complex and an extracellular needle together that form a continuous channel. Regulated secr...

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Autores principales: Lunelli, Michele, Hurwitz, Robert, Lambers, Jutta, Kolbe, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150277/
https://ncbi.nlm.nih.gov/pubmed/21829362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002163
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