Inhibition of PKMζ in Nucleus Accumbens Core Abolishes Long-Term Drug Reward Memory

During abstinence, memories of drug-associated cues persist for many months, and exposure to these cues often provokes relapse to drug use. The mechanisms underlying the maintenance of these memories are unknown. A constitutively active atypical protein kinase C (PKC) isozyme, protein kinase M ζ (PK...

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Main Authors: Li, Yan-qin, Xue, Yan-xue, He, Ying-ying, Li, Fang-qiong, Xue, Li-fen, Xu, Chun-mei, Sacktor, Todd Charlton, Shaham, Yavin, Lu, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150199/
https://ncbi.nlm.nih.gov/pubmed/21471379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5884-10.2011
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