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HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7

We recently reported that the endogenous ATP-binding cassette transporter (ABC) A7 strongly associates with phagocytosis, being regulated by sterol regulatory element binding protein 2. We therefore examined the effect of statins on phagocytosis in vitro and in vivo through the SREBP-ABCA7. Phagocyt...

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Detalhes bibliográficos
Main Authors: Tanaka, Nobukiyo, Abe-Dohmae, Sumiko, Iwamoto, Noriyuki, Fitzgerald, Michael L., Yokoyama, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150192/
https://ncbi.nlm.nih.gov/pubmed/21762915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.06.031
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