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Genetically Alterable Transport of Amethopterin in Diplococcus pneumoniae II. Impairment of the System Associated with Various Mutant Genotypes
Six mutations determining resistance to amethopterin were examined for their effects on the active transport of the drug. In strains bearing each of the mutations and exhibiting resistance levels varying from 10- to 100-fold, transport at limiting concentrations of H(3)-amethopterin was reduced from...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1967
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC315004/ https://ncbi.nlm.nih.gov/pubmed/4381316 |
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