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Genetically Alterable Transport of Amethopterin in Diplococcus pneumoniae II. Impairment of the System Associated with Various Mutant Genotypes

Six mutations determining resistance to amethopterin were examined for their effects on the active transport of the drug. In strains bearing each of the mutations and exhibiting resistance levels varying from 10- to 100-fold, transport at limiting concentrations of H(3)-amethopterin was reduced from...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Sirotnak, Francis M., Sargent, M. Gay, Hutchison, Dorris J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1967
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4381316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.93.1.315-319.1967
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