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Reversible aggregation of PABPN1 pre-inclusion structures
Increased aggregation of misfolded proteins is associated with aging, and characterizes a number of neurodegenerative disorders caused by homopolymeric amino acid expansion mutations. PABPN1 is an aggregation-prone nuclear protein. Natural aggregation of wild-type (WT) PABPN1 is not known to be dise...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149881/ https://ncbi.nlm.nih.gov/pubmed/21818414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.3.15736 |
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