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Safety and efficacy of targeted agents in metastatic kidney cancer patients with renal dysfunction
BACKGROUND: Multiple molecularly targeted agents (MTAs) have been approved for the management of metastatic renal cell carcinoma(mRCC). Sunitinib and M-TOR inhibitors (temsirolimus, everolimus) are primarily metabolized in the liver, while the metabolism of bevacizumab is unclear. There are limited...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149855/ https://ncbi.nlm.nih.gov/pubmed/21799472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e328346af0d |
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