Rescue of Impaired Fear Extinction and Normalization of Cortico-Amygdala Circuit Dysfunction in a Genetic Mouse Model by Dietary Zinc Restriction

Fear extinction is impaired in neuropsychiatric disorders, including posttraumatic stress disorder. Identifying drugs that facilitate fear extinction in animal models provides leads for novel pharmacological treatments for these disorders. Zinc (Zn) is expressed in neurons in a cortico-amygdala circ...

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Главные авторы: Whittle, Nigel, Hauschild, Markus, Lubec, Gert, Holmes, Andrew, Singewald, Nicolas
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149823/
https://ncbi.nlm.nih.gov/pubmed/20943900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0849-10.2010
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