Extended results of the Alzheimer disease anti-inflammatory prevention trial (ADAPT)

BACKGROUND: Epidemiologic evidence suggests that non-steroidal anti-inflammatory drugs (NSAIDs) delay onset of Alzheimer’s dementia (AD), but randomized trials show no benefit from NSAIDs in symptomatic AD. ADAPT randomized 2,528 elderly persons to naproxen or celecoxib vs. placebo for two years (s....

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Detalhes bibliográficos
Main Authors: Breitner, John C, Baker, Laura D, Montine, Thomas J, Meinert, Curtis L, Lyketsos, Constantine G, Ashe, Karen H, Brandt, Jason, Craft, Suzanne, Evans, Denis E, Green, Robert C, Ismail, M Saleem, Martin, Barbara K, Mullan, Michael J, Sabbagh, Marwan, Tariot, Pierre N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149804/
https://ncbi.nlm.nih.gov/pubmed/21784351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2010.12.014
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