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HER2-Affitoxin: A Potent Therapeutic Agent for the Treatment of HER2-Overexpressing Tumors

PURPOSE: Cancers overexpressing the HER2/neu gene are usually more aggressive and are associated with poor prognosis. Although trastuzumab has significantly improved the outcome, many tumors do not respond or acquire resistance to current therapies. To provide an alternative HER2-targeted therapy, w...

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Detalhes bibliográficos
Main Authors: Zielinski, Rafal, Lyakhov, Ilya, Hassan, Moinuddin, Kuban, Monika, Shafer-Weaver, Kimberly, Gandjbakhche, Amir, Capala, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149757/
https://ncbi.nlm.nih.gov/pubmed/21791637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2887
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